About HAE

HAE is a rare genetic condition characterized by unpredictable swelling. It can be life-threatening if the swelling blocks airways and prevents breathing.

What is hereditary angioedema (HAE)?

HAE is a rare genetic condition characterized by unpredictable swelling. It can be life-threatening if the swelling blocks airways and prevents breathing.

When you have HAE Type I or II, a gene called SERPING1, which makes the C1-INH protein (C1-inhibitor), is either not making enough protein (Type I) or is not working correctly (Type II). This protein is important in controlling certain types of swelling in the body.

Having not enough C1-INH protein in your body can cause HAE symptoms like:

representation of swelling in the face, airway (throat)

Swelling in the face, airway (throat), hands, arms, legs, and feet

representation of stomach pain

Stomach pain

representation of vomiting

Nausea or vomiting